Welcome

Dr. B. Vaseeharan’s lab research focusses on the Aquatic Animal Health Biotechnology, Crustacean Molecular Biology &Genomics, Molecular Biology & Immunology and Nanoscience &Technology. Our research team has sequenced the immune related genes of α2-macroglobulin, β-1, 3-glucan binding protein, serine proteinase, Fein-Penaeidin and penaeidin-3 from various crustaceans along the coastal waters of India. We constructed Green Fluorescent Protein (GFP) tagged Vibrio parahaemolyticus (shrimp pathogen) and reported the pathogen interactions and localization in the tissues of Fenneropenaeus indicus, that facilitate real-time monitoring of host–pathogen interactions which is the first report in India. Further, the complete sequence of α2M in Fenneropenaeus indicus was identified, gene expression of α2M after injections with GFP-tagged Vibrio parahaemolyticus and its regulation and localization were determined. Through this study the pathogen (Vibrio parahaemolyticus) entry was assessed and localized in the tissues of shrimps. Moreover, we use extracts of medicinal plants, probiotic bacteria, seaweeds and animal proteins to formulate nanocomposite with ZnONPs dietary supplements that enhance the immunity of the aquatic organisms. With this platform, we are using our research knowledge to build powerful contributions in research to improve the economic status of aqua industry through less toxic, low cost and eco-friendly probiotic, medicinal plant extract and prebiotic to enhance the immune system of aquatic organism and prevent the spread of disease in commercially important cultured species. Currently, we are working on the degradation of microplastics andassessing their toxicity in aquatic environment. Similarly, the impact of nanomaterials and pharmaceutical drugs and their adverse effects on aquatic organisms towards their metabolic capacity underexposure conditions and environmental changeswere analysed.Overall, Dr. B. Vasee’s lab works actively to enhance immunity, improving stress tolerance and disease resistance in aquatic animals under laboratory conditions which would help to achieve high yield in aqua farming and to protect the aquatic environment from toxic pollutants.